Mastering Skin Longevity
Mastering Skin Longevity
For 80 years, The Estée Lauder Companies has advanced skin science and innovation, including more than two decades of pioneering research into skin longevity.
Building on that legacy, in 2026 we unveiled Mastering Skin Longevity, a breakthrough scientific innovation platform designed to advance the next era of skin science and transformative product innovation.
Moving beyond the study of individual Hallmarks of Aging, Mastering Skin Longevity focuses further upstream on the Master Regulators of Skin Longevity, interconnected biological pathways and proteins that influence multiple hallmarks at once. By deepening our understanding of these systems and how they help support skin’s ability to repair, adapt and regenerate, Mastering Skin Longevity helps guide discovery across ingredients, technologies, formulations and future product innovation.
The Skin Longevity Clock
The Skin Longevity Clock brings Mastering Skin Longevity to life through a distinctive visual representation of the platform.
Inspired by the precision and interconnected mechanisms of a fine timepiece, the Clock illustrates how the Master Regulators work together to influence multiple Hallmarks of Aging, shaping processes associated with skin repair, adaptation, renewal and resilience over time.
Master Regulators: The Next Frontier in Skin Longevity
The Hallmarks of Aging help us understand the molecular and cellular changes associated with how skin ages over time. The Master Regulators take us further upstream, helping us investigate the interconnected biological systems that influence multiple hallmarks at once.
Today, scientists across The Estée Lauder Companies’ Longevity Labs in Melville and Shanghai are advancing research into Master Regulators including:
Studying these systems together creates a more integrated foundation for discovery and new opportunities across ingredients, technologies, formulations, and products.
Longevity Across Our Brands
Mastering Skin Longevity serves as a shared scientific foundation that brands across The Estée Lauder Companies apply through their distinct areas of expertise and product philosophies. Across the portfolio, brands explore longevity through different areas of focus...







