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Pioneering Skin Longevity Science

Pioneering Skin Longevity Science

For 80 years, The Estée Lauder Companies has defined the science of skin, pioneering foundational research in areas including skin’s biological age, circadian rhythm, sirtuins, and cellular energy. Now, we are advancing breakthrough science and research, delivering results that are reshaping the trajectory of how skin ages.

While the broader industry often focuses on individual hallmarks of aging, we at The Estée Lauder Companies are leading the science and conversation to enable skin to be at its peak performance and look its best at any age.

By advancing expertise across the master regulators of skin longevity coupled with our longstanding authority on the hallmarks of aging, The Estée Lauder Companies is building the scientific foundation to lead the next era of longevity science in support of long-term skin health, regeneration, resilience, and vitality.

Longevity Science by the Numbers 

80 Years of Breakthrough Skin Science

80 Years of Breakthrough Skin Science


A legacy of innovation and discovery, powered by global innovation centers and scientific expertise advancing next-generation skin care

20+ Years Pioneering Skin Longevity Research

20+ Years Pioneering Skin Longevity Research


We are the early leader decoding the biology of skin aging with Estée Lauder’s in-depth research of sirtuins, or “longevity proteins,” and their role in skin vitality and visible age reversal

50+ Years of Bio-Fermentation & Bio-Energetics Mastery

50+ Years of Bio-Fermentation & Bio-Energetics Mastery


Half a century of expertise rooted in La Mer’s Miracle Broth™, shaping our leadership in cellular energy and regenerative science

44 Patents Powering the Future of Longevity

44 Patents Powering the Future of Longevity


Breakthrough intellectual property spanning molecular pathways, rejuvenation technologies, and advanced delivery systems

60+ Scientific Publications

60+ Scientific Publications


A steady pipeline of research contributions that shape our understanding of skin longevity, backed by leading experts.

Longevity Across Our Brands

Across our diverse portfolio, our brands approach longevity in ways that are authentic to them, but always grounded in science, and deliver transformative products for consumers at every stage of their skin care journey.

Estée Lauder

A pioneering authority in skin longevity science, Estée Lauder has spent nearly two decades advancing research into sirtuins, epigenetics and biological age. Backed by more than 40 patents and collaborations with leading scientists and institutions, the brand is helping redefine the trajectory and quality of skin aging—marking a shift from traditional anti-aging toward a deeper understanding of the biological processes that influence how skin ages, looks and functions over time.

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La Mer

La Mer has long led the industry 
in fermentation, transforming the extraordinary energies of Giant Sea Kelp into Miracle Broth™—a 50-year legacy of bioenergetic science focused on cellular energy and the biological processes that support skin renewal. In 2025, La Mer began a 3-year partnership with the Salk Institute to advance scientific research into the role of mitochondria in healthy skin aging.

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Clinique

Backed by almost 6 decades of dermatological expertise, Clinique has clinically proven solutions to help slow skin’s signs of aging and build skin resilience. Through the Mount Sinai–Clinique Healthy Skin Dermatology Center, a multi-year philanthropic partnership, Clinique supports research to better understand the impact of allergic and sensitive skin on premature aging.

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The Ordinary

The Ordinary approaches skin longevity through a commitment to accessible, science-first care. Powered by evidence-based ingredients, our targeted formulations work to protect, support visible skin repair, and reinforce long-term resilience—maintaining skin integrity before visible signs of aging emerge.

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NIOD

NIOD looks at the inner workings of the skin: a dynamic organ, an intricate system of components 
that work in biological harmony to self-regulate. Each of our formulations is part of a system, too, meticulously crafted by our scientists to help optimize skin today and throughout the many stages of its life. This is how NIOD defines longevity. By leveraging technology, advancements in skin science and ingredients that work together with the skin, we offer a holistic approach, for skin that looks healthy, strong and resilient, for longer.

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